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Caleb and his six college pals are gearing up for an unforgettable Halloween bash when they inadvertently release a hidden biological serum in the quaint rural town of Lakeshear. This serum turns those exposed into frenzied, mindless killers. Unaware, Caleb becomes infected and must rally his friends to discover a remedy for this lethal contagion before time runs out. Who is behind the creation of this serum? And how far will these seven friends go to halt its deadly spread?